Santana went 1-for-4 with a three-run homer in Monday's 6-5 loss to Boston.
Santana gave the Royals an early lead with his three-run blast off Garrett Richards in the first inning. The veteran slugger is slashing .243/.365/.410 with 13 homers and 45 RBI on the year. He's hitting just .228 with three long balls in June.