Mondesi (hamstring) will start at shortstop and bat fifth in Wednesday's game against Detroit, Alec Lewis of The Athletic reports.
Mondesi was reinstated from the 10-day injured list ahead of Tuesday's game against the Tigers, but he didn't appear in the 4-3 loss. Prior to his second stint on the injured list, the 25-year-old hit .360 with two home runs, five RBI and a stolen base across seven games.