LeMahieu was removed from Sunday's game against the Diamondbacks due to a left knee contusion, MLB.com reports.
LeMahieu suffered the injury while trying to field a groundball in the sixth inning, and after a visit from team trainers, Daniel Descalsco replaced him at second base. The Rockies will likely turn to either Descalsco or Christian Adames if LeMahieu is unavailable for Monday's game against Toronto.