Antone will start Wednesday's game against the Indians, Bobby Nightengale of The Cincinnati Enquirer reports.
The Reds needed to adjust their rotation coming off the postponement and subsequent doubleheader over the weekend in Detroit, so Antone will step up for the spot start in Cleveland. The 26-year-old made his major-league debut July 27 against the Cubs and had a strong showing, allowing one run on one hit and a walk while striking out five over 4.1 innings.