The Reds placed Lodolo on the 15-day injured list Wednesday with left calf tenosynovitis.
Lodolo's stay on the IL shouldn't be much longer than the 15-day minimum, as he's already slated to pitch two games on a rehab assignment at Triple-A Louisville and will likely make his regular-season debut when eligible in mid-April. The 26-year-old southpaw appeared in two Cactus League games this spring, surrendering one earned run over 4.2 innings while striking out five batters and walking two.