Perez was recalled by the Reds on Wednesday.
Perez made 10 relief appearances for Cincinnati to begin the year and posted an 8.31 ERA and 1.62 WHIP in 8.2 innings. The southpaw pitched in Tuesday's season opener for Triple-A Louisville and allowed no hits and a walk while striking out two in one scoreless inning. He'll now return to the major-league bullpen after right-hander Jose De Leon was sent down in a corresponding move.