The Red Sox placed Mayer on the 10-day injured list Friday, retroactive to July 24, due to a sprained right wrist, Gabrielle Starr of the Boston Herald reports.
Mayer underwent an MRI on his wrist Thursday, and the evaluation determined he's dealing with a sprain. He'll require a stint on the injured list, opening up a spot on the 26-man roster for David Hamilton. Hamilton, Romy Gonzalez and Ceddanne Rafaela are the likeliest candidates to fill in for Mayer at second base.