Santana went 1-for-2 with a solo home run in Tuesday's 12-7 loss to Tampa Bay.
The 30-year-old entered the game with Boston trailing 12-3 in the eighth inning. Santana went back-to-back with Bobby Dalbec in the eighth, although the rally fell short. Santana missed two days while he was on the COVID-19 injured list, but his quick return indicates he is healthy. He'll likely continue to serve in a utility role. The veteran is slashing just .174/.250/.349 with five homers, 14 RBI, 14 runs scored and three stolen bases through 120 plate appearances.