Vazquez made a precautionary exit from Wednesday's game at Texas with left hamstring tightness, Pete Abraham of The Boston Globe reports.
Vazquez hit a two-run homer during the top of the third inning but did not retake the field for the bottom of the frame. The 29-year-old wasn't expected to start Thursday's contest regardless, but he could return for the final series of the season versus the Orioles this weekend.