Mesa (hamstring) will embark on a rehab assignment with Triple-A Durham on Wednesday, Ryan Bass of Rays.tv reports.
Mesa landed on the 10-day injured list Aug. 19 after aggravating a left hamstring injury. Rays manager Kevin Cash told reporters Monday that Mesa will play "a couple of games" in Durham, and if all goes well, the 24-year-old outfielder could be back with the parent club when eligible to come off the IL on Saturday.