Lowe is not in the lineup for Friday's game against Houston, Neil Solondz of the Rays Radio Network reports.
Lowe went 0-for-4 with one strikeout out of the cleanup spot in Thursday's season opener as the designated hitter. The 24-year-old can play both corner infield and outfield spots but will nonetheless take a seat Friday. Austin Meadows will be the designated hitter as Avisail Garcia starts in right field.