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Seymour is absent from the lineup for Wednesday's game in Cleveland, Ryan Bass of FanDuel Sports Network Sun reports.

Guardians right-handed starter Slade Cecconi has slight reverse splits, which helps explain why the left-handed-hitting Seymour will sit against a righty for the first time since he was promoted from Triple-A Durham earlier this month. Yandy Diaz will handle first base in Wednesday's rubber match.

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