The Pirates will face off against the Marlins with a number of moves whithin their lineup.
Catcher Francisco Cervelli, first baseman Pedro Alvarez and right fielder Gregory Polanco -- all regulars in the lineup -- will not start on Wednesday.
Alvarez went 1 for 4 with an RBI in his team's 5-1 win on Tuesday, but left four runners on base. Cervelli struck out twice and left two runners stranded. Polanco will be out of the starting lineup for the second consecutive game.