The Pirates designated Medina for assignment Wednesday.
Medina's removal from the 40-man roster clears a spot for the newly signed Andrew Knapp, who will open the season as the Pirates' No. 2 catcher. Meanwhile, Medina will be in DFA limbo for the second time this offseason, after the Phillies previously dropped him from their 40-man roster in December before he was claimed off waivers by the Pirates in March once the lockout concluded. If he clears waivers this time around, Medina will stick in Pittsburgh's organization and report to Triple-A Indianapolis.