Mize was removed during the third inning of Saturday's game against the Twins due to a right ankle sprain.
The velocity of Mize's pitches steadily decrease as Saturday's game went on, prompting his removal during the third frame. His next start is lined up for next weekend on the road against the Rays, but whether he's cleared to pitch will be determined by additional tests and how his ankle responds to treatment over the next few days. Mize was acquired by the Padres from the Tigers on the Aug. 3 trade deadline.