The Orioles designated Nittoli for assignment Friday, Roch Kubatko of MASNSports.com reports.
Nittoli will lose his spot on the Orioles' roster following the acquisition of Zach Eflin in a trade with Tampa Bay on Friday. The 33-year-old Nittoli has been a reliable option out of the bullpen this season, posting 1.50 ERA through 12 innings between the Athletics and Orioles, making it likely another team claims him off waivers.