The Orioles designated Luciano for assignment Thursday, Roch Kubatko of MASNSports.com reports.
Luciano will enter the waiver process for the second time this winter to create room on Baltimore's 40-man roster for Jose Suarez. Luciano, 24, slashed .214/.335/.413 across 555 plate appearances with the Giants' Triple-A affiliate last season and doesn't have any minor-league options remaining.