Sanders (1-0) earned the win after pitching a scoreless two-thirds of an inning while striking out one batter against the Astros on Friday.
Sanders was called on in a high-leverage situation in his Orioles debut. He entered the game in the seventh, facing a bases-loaded jam. After striking out Isaac Paredes and getting Christian Walker to pop out, the 29-year-old was in line for the win when Taylor Ward hit the go-ahead homer in the eighth.