Alexander was removed from Tuesday's game against the Guardians due to back spasms, Matt Weyrich of The Baltimore Sun reports.
Alexander went 1-for-3 with a run scored before his back forced him out of the game in the ninth inning. The team hasn't provided any details regarding the severity of his injury, but if the 27-year-old needs to miss time, Jackson Holliday would be next in line to start at second base.