Palmquist will serve as the Nationals' opening pitcher in front of Zack Littell during Saturday's game against the Pirates, Mark Zuckerman of NatsJournal.com reports.
Palmquist, who was recalled from Triple-A Rochester earlier this week, most recently logged an inning of relief in Boston on Wednesday. He'll likely be capped at an inning or two once again Saturday before giving way to Littell.