Vargas (elbow) will begin a rehab assignment at Double-A Akron on Sunday.
Vargas is ready to make his 2022 season debut after spending just under 14 months recovering from Tommy John surgery. The Guardians added Vargas to their 40-man roster during the offseason, but once he's activated from the 60-day injured list, he'll likely be optioned to Akron and continue to make regular starts for the affiliate.