DeSclafani was removed from his start Wednesday against the Mets in the second inning due to an apparent physical concern, Kerry Crowley of The San Jose Mercury News reports. He struck out a batter over 1.1 scoreless innings and gave up a hit and issued a walk before departing.

Justice delos Santos of MLB.com notes that DeSclafani's final fastball of the afternoon clocked in at 90.7 miles per hour, a dip of about four or five mph from where it sat in the first inning. The sharp drop in velocity likely hints at some kind of arm issue, but the Giants should provide more clarity on that front after the game once tests are conducted. Given that DeSclafani was on the injured list with right shoulder fatigue before being activated ahead of his last start Aug. 13 versus Colorado, it wouldn't be surprising if he experienced a setback Wednesday.