Kershaw will make his season debut Wednesday against the Twins, David Vassegh of AM 570 LA Sports reports.
Walker Buehler, Tony Gonsolin and Julio Urias are starting during the season-opening series in Colorado, and Kershaw will take the ball for the second game of the series in Minnesota. The veteran left-hander appears to be fully healthy and threw 75 pitches in a simulated game Thursday, so he shouldn't face any significant restrictions in his first start of 2022.