Holton was recalled from Triple-A Reno on Friday.
Holton had his contract selected by Arizona in late April, and he was sent back to Reno a day later after delivering a scoreless frame in his major-league debut. The left-hander has struggled early in the season at Triple-A this year with a 5.65 ERA, 1.70 WHIP and 14:9 K:BB across 14.1 innings.