Perdomo went 2-for-6 with a run scored in Wednesday's 6-4 loss to the Rockies.
Perdomo was back at shortstop and led off for the Diamondbacks after missing one game due to a knee issue. The multi-hit effort was his sixth in the last 12 contests, during which Perdomo is 18-for-48 (.375) with four extra-base hits (one home run), five RBI and six runs scored.