Leone was optioned to Triple-A Reno on Thursday.
Aside from a three-run meltdown against the Mets on Aug. 17, Leone had been solid out of the pen over the past two weeks. However, he had been used quite a bit of late, so the Diamondbacks optioned him and Steve Hathaway to get some fresh arms back up to the bullpen. Leone could rejoin the club once rosters expand next week.