The Diamondbacks placed Mena (shoulder) on the 60-day injured list Wednesday.
Mena didn't pitch after June 6 last season after straining his right shoulder and had received a clean bill of health heading into spring training before aggravating the injury early in camp. The right-hander remains shut down from throwing and will now be shelved for at least the first two months of the season while he continues to rehab the injury.