Prieto will start at third base and bat ninth in Friday's contest versus the Cubs.
It's the fifth start over the last six games against right-handers for Prieto, who picked up his first hit of the season in Wednesday's win over the Phillies. The 27-year-old infielder is just 2-for-34 so far at the major-league level but has been a steady performer at Triple-A Memphis, slashing .307/.373/.517 with 12 homers and a 25:38 BB:K over 71 games there this season.