Lukes was removed from Friday's game against the Guardians with left hamstring discomfort, Keegan Matheson of MLB.com reports.
Lukes hit a double to lead off the first inning but apparently tweaked his hamstring while running and was replaced on the bases immediately afterward. The severity of his injury remains unknown, but if he ends up needing to miss additional time, Myles Straw would be in line to make extra starts in the outfield.