Okamoto went 1-for-2 with a homer and two runs scored in Toronto's 8-6 loss to Washington on Tuesday.
After replacing the injured Vladimir Guerrero (hamstring) at first base in the bottom of the fourth inning, Okamoto clubbed a pinch-hit homer in his first at-bat in the fifth. The 30-year-old later came around to score on George Springer's three-run homer in the eighth. On the campaign, Okamoto is slashing .226/.304/.449 with 24 homers and 66 RBI in 427 plate appearances. If Guerrero is to miss time, Okamoto would likely receive more playing time at first base.