Donaldson was removed from Wednesday's game versus the Rays in the seventh inning, Gregor Chisholm of MLB.com reports.
Donaldson seemed to be limping a bit earlier in the game, and it appears that there may actually be an issue of some sort. What's wrong is currently unknown, but more information about the possible ailment and severity should come soon. Darwin Barney took over at third base following Donaldson's exit.