Vasquez was optioned to Triple-A Buffalo on Monday, Keegan Matheson of MLB.com reports.
Vasquez inked a deal with Toronto on March 11 with the hope of cracking the Opening Day roster, but he'll begin 2022 in the minors following Monday's transaction. He made five relief appearances for the Blue Jays this spring, allowing two runs on three hits and one walk while fanning five over 3.1 frames.