Reed is not in the lineup for Friday's game against the Mariners, Greg Johns of MLB.com reports.
Marwin Gonzalez will get the nod at first base with the Astros facing lefty James Paxton to kick off the second half. The 23-year-old Reed hasn't exactly hit the ground running since his promotion from Triple-A (5-for-35, 16 strikeouts), but the Astros figure to let the slugger learn on the job while serving on the large end of a first-base platoon.