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Ohtani will serve as the team's designated hitter Friday and could Saturday as well, Fabian Ardaya of The Athletic reports.

Ohtani's status was uncertain after he dealt with a blister earlier in the week, but he's in the Opening Day lineup and appears headed for a full workload. In addition to his DH duties, Ohtani is slated to make his debut on the mound Sunday, and he won't have a pitch limit despite not being fully stretched out.

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