Rendon left Tuesday's game against the Cubs after the fifth inning, Sam Blum of The Athletic reports. He went 0-for-2 with a walk before exiting.
Rendon's exit comes after he was activated off the injured list by the Angels earlier in the day, and it's not known if the move is injury-related at this time. Jared Walsh has taken over Rendon's spot in the lineup with Gio Urshela moving to third and Walsh now playing first.