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Liverpool and Manchester United meeting is always a marquee fixture, even if it has been years since the duo were both battling for top four spots, and this Sunday will be no different. After going into the international break on the back of a victory, United will want to show that things are moving in the right direction under Ruben Amorim, while Liverpool will want to end their run of three consecutive defeats in all competitions. A return to Anfield will be a good sign for the Reds, considering that all of these defeats came away from home. That'll make for an entertaining scene at Anfield, but here are a few things to watch out for.

How to watch Tottenham vs. Aston Villa, odds

  • Date: Sunday, Oct. 19 | Time: 11:30 a.m. ET
  • Location: Anfield -- Liverpool, England
  • TV: USA | Live stream: Fubo (Try for free)
  • Odds: Liverpool -15; Draw +350; Manchester United +420

Does Florian Wirtz start?

It's no secret that Florian Wirtz has had a tough time adjusting to Liverpool, and in the loss to Chelsea, he did begin the match on the bench after it was time for Slot to try something new. But when Wirtz came on for the second half of play, while he may not have registered an assist, it was one of his most promising periods of time playing despite the loss. When Wirtz came on, he had a deft interplay with Cody Gakpo and Mohamed Salah. While that didn't lead to a goal, it showed how fluid things can be with Wirtz at his best. 

Facing a United side who are struggling for consistency, and with the return home, it could be a good chance for Slot to see if Wirtz can build on that. Liverpool's ceiling will be raised if they can get him going, and if a match like this isn't a spot to build on things, it'll be tough to see what is.

Through Amad, all things are possible

The young United attacker may only have one assist so far this season, but every United win has come with him in the starting XI. After a breakout season under Amorim last campaign, new signings Bryan Mbuemo and Matheus Cunha have made it tougher to fit Diallo into the XI, but it's clear that he needs to be in the XI. After Bruno Fernandes, United lack creativity, while Diallo's shots also keep goalkeepers honest. In the victory over Sunderland, it was Cunha who came off the bench so that Diallo could play in an advanced position, and if United are going to find a victory at Anfield, he'll need to be involved.

Where is Alexander Isak?

Both Liverpool and Sweden are wondering the answer to this question. His offseason transfer saga impacted his fitness, and now, in-season, when Isak is needed to lead the line for club and country, the results aren't there. With only one goal and one assist in six appearances for Liverpool in all competitions, this isn't what Liverpool spent more than 100 million on. It's still early, but if Isak can't get back to last season's form, which saw him score 24 Premier League goals, the Reds may not reach the heights they hope to reach.