Friday, October 31, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| J. BrendelJake Brendel | C | Fri, Oct 31 | Hamstring | Out for Week 9 at N.Y. Giants. Expected Return - Week 10 |
| B. HuffBryce Huff | DE | Fri, Oct 31 | Hamstring | Out for Week 9 at N.Y. Giants. Expected Return - Week 10 |
| Y. Gross-MatosYetur Gross-Matos | DE | Fri, Oct 31 | Knee | Out for Week 9 at N.Y. Giants. Expected Return - Week 10 |
| R. PearsallRicky Pearsall | WR | Fri, Oct 31 | Knee - PCL | Out for Week 9 at N.Y. Giants. Expected Return - Week 10 |
Wednesday, October 29, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| B. BartchBen Bartch | OT | Wed, Oct 29 | Ankle | IR. Injured Reserve. Expected Return - Week 9 |
Monday, October 27, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| B. PurdyBrock Purdy | QB | Mon, Oct 27 | Toe | Limited Practice on Friday. Questionable for Week 9 at N.Y. Giants |
Sunday, October 26, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| K. RourkeKurtis Rourke | QB | Sun, Oct 26 | Knee | NFI-R for Week 9 at N.Y. Giants |
| J. ElliottJordan Elliott | DT | Sun, Oct 26 | Ankle | Did Not Practice on Friday. Questionable for Week 9 at N.Y. Giants |
| J. CowingJacob Cowing | WR | Sun, Oct 26 | Hamstring | IR. Injured Reserve. Expected Return - Week 9 |
| S. OkuayinonuSam Okuayinonu | DT | Sun, Oct 26 | Ankle | Limited Practice on Friday. Questionable for Week 9 at N.Y. Giants |
| D. WintersDee Winters | LB | Sun, Oct 26 | Knee | Limited Practice on Friday. Questionable for Week 9 at N.Y. Giants |
Saturday, October 25, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| S. BurfordSpencer Burford | OT | Sat, Oct 25 | Knee | IR. Injured Reserve. Expected Return - Week 9 |
Thursday, October 23, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| B. AiyukBrandon Aiyuk | WR | Thu, Oct 23 | Knee - ACL + MCL | Physically Unable to Perform. Expected Return - Week 9 |
Saturday, October 18, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| T. JacksonTarron Jackson | DE | Sat, Oct 18 | Undisclosed | IR. Injured Reserve |
| F. WarnerFred Warner | MLB | Sat, Oct 18 | Ankle | IR. Injured Reserve |
Wednesday, October 1, 2025
| Player | Position | Updated | Injury | Injury Status |
|---|---|---|---|---|
| T. Hodges-TomlinsonTre'Vius Hodges-Tomlinson | CB | Wed, Oct 1 | Undisclosed | IR. Injured Reserve |
| T. TaylorTrent Taylor | WR | Wed, Oct 1 | Undisclosed | IR. Injured Reserve |
| P. TaylorPatrick Taylor | RB | Wed, Oct 1 | Shoulder | IR. Injured Reserve |
| J. RobinsonJakob Robinson | CB | Wed, Oct 1 | Forearm | IR. Injured Reserve |