Brendel (hamstring) was ruled out ahead of Sunday's matchup against the Giants,Jennifer Lee Chan of NBC Sports Bay Area reports.
Brendel originally suffered the injury in Week 7 against the Falcons and will be set for his second consecutive absence. He has yet to practice since getting hurt.
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49ers' Jake Brendel: Sits out practice
Rotowire
Brendel (hamstring) didn't participate in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Brendel remains sidelined with the knee injury he suffered in the team's Week 7 win over the Falcons. Matt Hennessy will start at center for the second straight week if Brendel is unable to suit up for Sunday's matchup against the Giants.
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49ers' Jake Brendel: Won't play Sunday
Rotowire
Brendel (hamstring) is listed as out for Sunday's game at Houston, Nick Wagoner of ESPN.com reports.
Brendel will miss his first game of the season in Week 8 due to a hamstring injury he suffered in Week 7 versus the Falcons. In his absence, Matt Hennessy projects to start at center Sunday at Houston.
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49ers' Jake Brendel: Ruled out Sunday night
Rotowire
Brendel has a hamstring injury and has been ruled out for the rest of Sunday night's matchup with the Falcons, Matt Maiocco of NBC Sports Bay Area reports.
The veteran has started all seven games this season and every 49ers game dating back to 2021. Matt Hennessy is his backup.
