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Eleven more NFL games are set for Sunday afternoon either in the 1 p.m. ET or 4:05/4:25 p.m. ET window, and those matchups comprise the main slate for NFL DFS sites like FanDuel and DraftKings. The final kickoff on the slate, Chiefs vs. Bills, also has the highest over/under of the day at 52.5 points. Big names like Josh Allen, Patrick Mahomes, James Cook and Travis Kelce will certainly be a factor in NFL DFS lineups.

How should they factor into your NFL DFS picks this week, and who are the sleepers in the NFL DFS player pool that can help differentiate your lineups? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine's advanced NFL DFS lineup optimizer.

New users can also target the latest Underdog promo code, where they can pick at Underdog and get $100 in site credits after making a $5 wager:

The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool for sports betting apps.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2025 NFL Week 9 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

New users can get $50 in Pick6 credits at DraftKings when they play $5.

Top NFL Week 9 DFS picks for Sunday

One of the optimizer's top DFS value picks for Sunday is Bears quarterback Caleb Williams at $5,700 on DraftKings and $7,300 on FanDuel. Williams has been trending down the past couple weeks, with two games in a row with no touchdowns and an interception in both. He's also totaled just 20 rushing yards over the past three weeks.

That's lowered his DFS price, but this is an ideal spot to use him as a value pick as the Bears take on the Bengals. Cincinnati has been one of the worst passing defenses in the league recently as opposed defenses have feasted against the Bengals. See who else to pick here.

The optimizer's NFL DFS strategy also includes building around 49ers running back Christian McCaffrey, who is $9,500 on FanDuel and $8,800 on DraftKings. McCaffrey missed some practice earlier this week, but that turned out to be for rest and precautionary reasons, as he's full go for Sunday against the Giants.

New York is tied for 25th in terms of most Fantasy points given up to opposing backs this season, so McCaffrey is in a great bounce-back spot after a slow week against the Texans in Week 8. You can see the rest of the optimizer's NFL DFS picks here.

New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins

How to build Sunday Week 9 NFL DFS lineups

The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the optimizer's NFL DFS picks, at SportsLine

So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS optimizer that simulates every game 10,000 times, and find out.