bijan-robinson-atlanta-falcons
Imagn Images

There are no international games in Week 12, so 11 more NFL games are set for Sunday afternoon either in the 1 p.m. ET or 4:05/4:25 p.m. ET window. Those matchups comprise what is considered the main slate for NFL DFS sites like FanDuel and DraftKings. Two games -- Lions vs. Giants and Chiefs vs. Colts -- have an over/under of 50 or higher, meaning they'll be a focus for NFL daily Fantasy players with big names like Patrick Mahomes, Travis Kelce, Daniel Jones, Jonathan Taylor and Amon-Ra St. Brown in action. Some big names will be missing, however, as Joe Burrow (toe) won't return yet and Cincinnati's top receiver, Ja'Marr Chase, is serving a one-game suspension. 

How should all that NFL news factor into your NFL DFS picks this week, and who are the sleepers in the NFL DFS player pool that can help differentiate your lineups? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine's advanced NFL DFS lineup optimizer.

New users can also target the latest Underdog promo code, good for $100 in bonus entries when you play $5 with the promo code CBSSPORTS2 in select states.

The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2025 NFL Week 12 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

New users can get $50 in Pick6 credits at DraftKings when they play $5.

Top NFL Week 12 DFS picks for Sunday

One of the optimizer's top DFS value picks for Sunday is New England Patriots quarterback Drake Maye at $6,900 on DraftKings and $8,400 on FanDuel. Maye is in the MVP conversation this season thanks to him leading the NFL with 2,836 passing yards and ranking fifth in touchdowns (20). He's also added value as a runner with 285 yards and two scores. Patriots vs. Bengals has an over/under of 49.5, and the Bengals have given up the second-most Fantasy points to opposing QBs, making this a dream matchup for Maye. See who else to pick here.

The optimizer's NFL DFS strategy also includes building around Falcons running back Bijan Robinson at $8,500 on DraftKings and $9,600 on FanDuel. Robinson had 143 scrimmage yards and two scores last week. Now he takes on a New Orleans defense that ranks 20th in the league in both yards and Fantasy points given up to opposing running backs. With quarterback Michael Penix Jr. (knee) out for the year, top receiver Drake London (knee) ruled out this week, Robinson should be an even bigger focal points for this offense. You can see the rest of the optimizer's NFL DFS picks here.

New users can also check out the latest FanDuel promo code and get $150 in bonus bets at FanDuel if your $5 bet wins. 

How to build Sunday Week 12 NFL DFS lineups

The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the optimizer's NFL DFS picks, at SportsLine. 

So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS optimizer that simulates every game 10,000 times, and find out.