Skip to Main Content
Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you.

Lions vs. 49ers Live updates Score, results, highlights, for Sunday's NFL game

The San Francisco 49ers and the Detroit Lions will face off at 1 p.m. ET Sept. 12 at Ford Field to kick off their 2021 seasons. San Francisco struggled last year, ending up 6-10. Likewise, last year was nothing to brag about for Detroit (5-11), either, so the team is looking forward to a new start.

A couple defensive numbers to keep in mind before kickoff: The 49ers were fourth best in rushing touchdowns allowed, finishing the 2020 season giving up only 12. Less enviably, Detroit ranked worst with respect to touchdowns allowed last season, where the squad gave up 65. The good news for Detroit, of course, is that these forces working against them might not carry over into the new season.

San Francisco has the odds in their favor, so they'll need to guard against complacency. A victory is hardly a sure thing, especially this early in the season, so expect a good game.

Updates
(96)
See New Posts
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:55 PM
Sep. 12, 2021, 4:55 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:51 PM
Sep. 12, 2021, 4:51 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:42 PM
Sep. 12, 2021, 4:42 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:41 PM
Sep. 12, 2021, 4:41 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:27 PM
Sep. 12, 2021, 4:27 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:26 PM
Sep. 12, 2021, 4:26 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:20 PM
Sep. 12, 2021, 4:20 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:17 PM
Sep. 12, 2021, 4:17 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:14 PM
Sep. 12, 2021, 4:14 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:14 PM
Sep. 12, 2021, 4:14 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:09 PM
Sep. 12, 2021, 4:09 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:07 PM
Sep. 12, 2021, 4:07 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:07 PM
Sep. 12, 2021, 4:07 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:06 PM
Sep. 12, 2021, 4:06 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:54 PM
Sep. 12, 2021, 3:54 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:40 PM
Sep. 12, 2021, 3:40 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:31 PM
Sep. 12, 2021, 3:31 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:27 PM
Sep. 12, 2021, 3:27 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:27 PM
Sep. 12, 2021, 3:27 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:19 PM
Sep. 12, 2021, 3:19 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:19 PM
Sep. 12, 2021, 3:19 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:17 PM
Sep. 12, 2021, 3:17 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:11 PM
Sep. 12, 2021, 3:11 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:09 PM
Sep. 12, 2021, 3:09 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:54 PM
Sep. 12, 2021, 2:54 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:47 PM
Sep. 12, 2021, 2:47 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 6:46 PM
Sep. 12, 2021, 2:46 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:32 PM
Sep. 12, 2021, 2:32 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 6:32 PM
Sep. 12, 2021, 2:32 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:30 PM
Sep. 12, 2021, 2:30 pm EDT
See More
default-cbs-image
Now Playing

Share Video

Link copied!
  • Image thumbnail
    1:52

    More Concerned With Lions' Coordinators Or Packers' DBs?

  • Image thumbnail
    1:09

    More Concerned With Bengals Defense Or Steelers O-Line?

  • Image thumbnail
    1:50

    NFL News & Notes: Most Surprising Cut in NFL on Tuesday in NFC

  • Image thumbnail
    1:23

    NFL News and Notes: Spencer Rattler Named Saints Week 1 Starting QB

  • Image thumbnail
    0:55

    NFL News and Notes: Shedeur Sanders Opens Season as QB3 In Cleveland

  • Image thumbnail
    3:07

    NFL News and Notes: Dillon Gabriel gets QB2 nod over Shedeur Sanders in Cleveland

  • Image thumbnail
    2:53

    NFL News & Notes: Most Surprising Player Cut on Tuesday in AFC

  • Image thumbnail
    1:25

    Examining the Importance of the "Cap" on Cutdown Day

  • Image thumbnail
    1:11

    Browns Trade Kenny Pickett to Raiders

  • Image thumbnail
    1:08

    Falcons Move Forward With Kirk Cousins As Backup QB

  • Image thumbnail
    0:56

    More Concerned With Saints Or Browns Quarterback Situation?

  • Image thumbnail
    0:56

    More Concerned With Buccaneers WRs Or Falcons Pass Rush?

  • Image thumbnail
    0:56

    More Concerned With Patriots WRs Or Dolphins O-Line?

  • Image thumbnail
    0:54

    Should The Dolphins Move On From Tyreek Hill?

  • Image thumbnail
    0:45

    Browns Cut Wide Receiver Diontae Johnson

  • Image thumbnail
    1:46

    Will This Season Be Travis Kelce's Last Dance?

  • Image thumbnail
    1:18

    Breece Hall Entering Final Year of Deal

  • Image thumbnail
    0:53

    Titans Cut Wide Receiver Xavier Restrepo

  • Image thumbnail
    1:11

    Why Drew Allar Is Mike Renner's No.5 QB In His 2026 NFL Draft QB Rankings

  • Image thumbnail
    0:29

    BREAKING: Spencer Rattler Named Saints Starting QB