Commanders vs. Bears prediction, odds, start time: 2025 Week 6 Monday Night Football picks from proven model

The Chicago Bears (2-2) visit the Washington Commanders (3-2) in the NFL Week 6 finale on 'Monday Night Football.' The Bears are coming out of their Week 5 bye looking for another victory after winning each of their last two games. They visit a Commanders team that upset the Los Angeles Chargers in a 27-10 road win their last time out. Tight end Noah Brown (groin/knee) and receiver Terry McLaurin (quad) are out for Washington.

Kickoff from Northwest Stadium is set for 8:15 p.m. ET. Washington is a 5.5-point favorite in the latest Bears vs. Commanders odds, and the over/under for total points scored is 49.5. Before making any Commanders vs. Bears picks, be sure to see what the SportsLine projection model has to say. 

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The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 41-21 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.  

Now, the model has zeroed in on Commanders vs. Bears. You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Bears vs. Commanders on Monday Night Football:

Why the Bears can cover

Chicago last played on September 28, and has had extended time to prepare for this matchup. The offense is generating just under 330 yards per game and will face a Commanders defense that is allowing north of 350. 

Caleb Williams has an 8-2 TD-INT ration through four games and the Bears should be able to run the ball against a Commanders defense that has been inconsistent against the rush. See which team to back at SportsLine. 

Why the Commanders can cover

Washington is 7-2-0 ATS over its last nine games and 5-0-0 ATS in its last five at home. Jayden Daniels missed two games due to a knee injury and has just a 59.2 completion percentage, although he has yet to turn the ball over this season. He threw for 231 yards against the Chargers and could have his best game of the season against a Bears defense that is allowing 379.5 total yards per game. 

The Bears have had a particularly hard time defending the rush, which could open the door for rookie Jacory Croskey-Merritt to have another big game. See which team to back at SportsLine. 

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How to make Commanders vs. Bears picks

For Monday Night Football in NFL Week 6, the model is leaning over the total, and also says one side of the spread hits in over 50% of simulations. See what it is at SportsLine.

Who wins Bears vs. Commanders, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the Commanders vs. Bears spread you need to jump, all from the model that is 41-21 on top-rated picks since 2024, and find out.