49ers inactives vs. Seahawks
T Joe Looney (concussion) is active, but WR Mario Manningham is not. RB Brandon Jacobs will suit up for the first time as a 49er.
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49ers inactives: WR Mario Manningham (shoulder), QB Scott Tolzien, WR A.J. Jenkins, RB LaMichael James, S Trenton Robinson, G Joe Looney, NT Ian Williams.
LT Joe Staley will play despite suffering a concussion Sunday against the New York Giants, and RB Brandon Jacobs will make his debut for the 49ers.
Follow 49ers reporter Kyle Bonagura on Twitter @CBS49ers and @KyleBonagura.