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The 2025-26 NBA season rolls on Tuesday with five more matchups. The first tip comes at 7 p.m. ET as the Philadelphia 76ers (-3.5) take on the Washington Wizards. Philadelphia is off to a 3-0 start, and rookie guard VJ Edgecombe has been a star with 24.5 points per game thus far. He has an over/under of 19.5 points on Tuesday. 

Other notable NBA lines on Tuesday include Knicks (-1.5) vs. Bucks at 8 p.m. ET and Clippers (-2.5) vs. the Warriors at 11 p.m. ET. What are the best NBA bets on the board? Before locking in any NBA picks, you'll want to see the NBA predictions and betting advice from SportsLine's proven computer model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past seven-plus seasons. The model enters Week 2 of the 2025-26 NBA season on a sizzling 161-120 roll on all top-rated NBA picks, returning nearly $4,000. It also went 24-11 (69%) on top-rated NBA against-the-spread picks last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has scoured the latest NBA odds and locked in three confident NBA best bets. If you successfully parlay its picks, you'd be looking at a payout of just under +600. You can only see the model's NBA picks at SportsLine.

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Top NBA picks for Tuesday, Oct. 28

After simulating every game 10,000 times, the model is going Over 225.5 in the 11 p.m. ET tip between the Warriors and Clippers. Bradley Beal (back) is out for the Clippers, while the Warriors haven't released their injury report yet. 

The Warriors have gone Over the total in all four of their games thus far, while the Clippers are 2-1 to the Over. SportsLine's model projects that the teams combine for 234 points as the Over hits in 64% of simulations. See which other NBA parlay picks to make here, and bet this pick right here:

How to make NBA predictions for Tuesday, October 28

The model also has locked in two other picks, both of which hit well over 60% of the time in the simulations. You can only see the model's NBA parlay at SportsLine.

What are the model's top NBA parlay picks for Tuesday, and which best bets should you target for a chance at a payout of nearly +600. Visit SportsLine now to see NBA best bets from a model that's returned more than $4,000 on top-rated picks, and find out.