Celtics vs. 76ers odds, prediction, line, time: 2025 NBA picks for Tuesday, November 11 from proven model

Eastern Conference foes meet on Tuesday as the Boston Celtics travel to take on the Philadelphia 76ers. The Sixers are 6-4 this season with an impressive 8-1-1 record against the spread. Boston is below .500 both straight up (5-6) and ATS (4-7). Paul George (knee) remains out for Philadelphia, while Jayson Tatum (Achilles recovery) is the only major absence for Boston. 

Tipoff is set for 8 p.m. ET. Philadelphia is a 1.5-point home favorite in the latest 76ers vs. Celtics odds, while the over/under is 231.5. Before making an Celtics vs. 76ers picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

New users can target the DraftKings promo code, which offers $300 in bonus bets if your bet wins + 3 months of NBA League Pass:

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 4 of the 2025-26 NBA season on a sizzling 26-13 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated 76ers vs. Celtics 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Celtics vs. 76ers:

How to make Celtics vs. 76ers picks

SportsLine's model has simulated Celtics vs. 76ers 10,000 times and is going Under 231.5 combined points. Both teams went Under in their last game, and when the line is set in this range (231-234 points), these teams have gone Under five times in seven opportunities this season. 

Both teams are projected to have just one player score more than 20 points as Jaylen Brown goes for 24.5 points in the simulations, while Tyrese Maxey has 25.5

The teams combine for 228 points as the Under hits in nearly 60% of simulations. 

The model also says one side of the spread hits nearly 60% of the time. You can head to SportsLine to see the model's NBA picks. 

So who wins Celtics vs. 76ers, and which side of the spread is the better value? Visit SportsLine now to see which side of the spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.