Mrazek will be between the visiting pipes in Buffalo on Friday, Heather Engel of NHL.com reports.
Mrazek has not played in seven of Chicago's last eight games due to a groin injury and was rusty in his first appearance back, as he allowed five goals on 29 shots in a 6-4 loss to Calgary. Mrazek is 7-12-1 with a 2.95 GAA and a .902 save percentage across 21 contests this season. The Sabres are tied for 30th overall in the NHL standings and have averaged 2.94 goals per game this season.