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Jayden Daniels and Bo Nix are both coming off exceptional rookie seasons but rookie quarterbacks are typically boom or bust for Fantasy football managers. Cam Ward was the No. 1 overall pick in the 2025 NFL Draft and he's the Day 1 starter in Tennessee. However, the Titans offense is lacking in playmakers and this year's QB class is generally accepted as one of the weaker in recent memory.

So how will Ward fare this season, and who are some of the 2025 Fantasy football breakouts that you need to be looking out for? A reliable set of live-updated 2025 Fantasy football rankings can provide answers to those pressing questions ahead of your upcoming drafts. Before crafting your 2025 Fantasy football draft strategy, be sure to check out the 2025 Fantasy football rankings and cheat sheets from the proven computer model at SportsLine.

Last year, the model accurately predicted that Commanders quarterback Jayden Daniels would comfortably outperform his ADP (QB13). The result: Daniels threw for 3,568 yards and 25 touchdowns with only nine interceptions and added 891 rushing yards with six more scores on the ground to take home NFL Offensive Rookie of the Year honors. He finished as QB5 in CBS Sports PPR leagues and was a great addition to Fantasy football lineups.

The same model has a proven track record providing Fantasy football tips, identifying A.J. Brown as a sleeper in 2020, nailing Jonathan Taylor's monstrous season in 2021 and correctly predicting C.J. Stroud would take a step back in 2024. Additionally, it's called past Fantasy football sleepers like Derrick Henry in 2019, Christian McCaffrey and Alvin Kamara in 2018, and Davante Adams in 2017. Anybody who banked on players like those made a run at their league title.

Now, SportsLine has simulated the entire NFL season 10,000 times and released its latest Fantasy football rankings 2025, along with plenty of sleepers, breakouts and busts. Head to SportsLine now to see them. 

Top 2025 Fantasy football breakouts

One of the 2025 Fantasy football breakouts the model is predicting: Bears wide receiver Rome Odunze. The second-year wideout finished as the Fantasy WR47 last season, which was disappointing after he went off the board as the WR34 in ADP data. Odunze finished with 54 receptions for 734 yards and three touchdowns, averaging 43.2 receiving yards per game.

He played in a dysfunctional Chicago offense, but offensive coordinator Shane Waldron and wide receiver Keenan Allen are both gone. Head coach Ben Johnson should improve the offense this season, and Odunze could wind up as quarterback Caleb Williams' go-to option. The model has Odunze ranked ahead of wide receivers Rashod Bateman, Chris Olave and Keon Coleman, among others. 

Another potential breakout that SportsLine's Fantasy football rankings 2025 have identified: Chargers running back Omarion Hampton. Jim Harbaugh's teams have always been dedicated to running the football and the Chargers completely revamped their running back room this offseason by signing Najee Harris and drafting Hampton in the first round. News this week that Harris was likely to begin his season on the NFI list after a fireworks incident on the Fourth of July should give Hampton needed reps in training camp.

The North Carolina product rushed for 3,164 yards and 30 touchdowns in his final two seasons in Chapel Hill and then he tested well at the NFL Scouting Combine, running a 4.46-second 40-yard-dash at 221 pounds while showcasing his explosiveness with a 38-inch vertical and a 10-foot-10 broad jump. He has an ideal blend of size, strength and aggressiveness to play for Harbaugh and the model ranks him as a top-25 back for 2025. See which other Fantasy football breakouts 2025 to pick here.

How to find proven 2025 Fantasy football rankings

SportsLine is also extremely high on a rookie running back to make an immediate impact. The model ranks this player as a top-10 option ahead of more established stars like Christian McCaffrey and Bucky Irving. You can only see who it is, and the 2025 Fantasy football rankings for every player, at SportsLine.

So which 2025 Fantasy Football breakouts should you target, and which RB shocks the NFL with a top-10 performance? Visit SportsLine now to get 2025 Fantasy Football cheat sheets for every single position, all from the model that called Jayden Daniels' breakout rookie season, and find out.

2025 Fantasy football ADP

(PPR, via CBS)

1. Ja'Marr Chase (1.68)
2. Bijan Robinson (2.54)
3. Saquon Barkley (3.15)
4. Jahmyr Gibbs (3.91)
5. CeeDee Lamb (7.23)
6. Justin Jefferson (7.44)
7. Derrick Henry (7.99)
8. Christian McCaffrey (9.02)
9. Ashton Jeanty (11.65)
10. Josh Jacobs (11.95)