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James (coach's decision) is inactive for Sunday's game against the Jaguars, Briana Jeannel of the 49ers' official site reports.

James will be a healthy scratch for the third week in a row. With the rookie fifth-rounder inactive, Brian Robinson and Isaac Guerendo will serve as the backup running backs behind starter Christian McCaffrey. James also missed Week 1 with a finger injury, so his next opportunity to make his NFL regular-season debut will come Week 5 versus the Rams on Thursday, Oct. 2.

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