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In order to put together a championship-caliber Fantasy football team, players need to have strong wide receiver and running back positional groups to go along with a solid quarterback and good tight end play. Kickers and defense are important, but rounding out the other areas of your team should be your top priority. Targeting top running backs first may be best, since production levels tail off the longer you wait. The wide receiver group also has more players to choose from.

Last year was a good example of just how deep the wide receiver depth in a Fantasy football draft can be. DeAndre Hopkins ranked 50th in positional Fantasy points, but finished ahead in scoring over a number of top-40 Fantasy running backs and tight ends. In order to ensure Fantasy football success, you need to have the most up-to-date 2025 Fantasy football advice you can get. Before crafting your 2025 Fantasy football draft strategy, be sure to check out the 2025 Fantasy football positional rankings and cheat sheets from the proven computer model at SportsLine.

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Last year, the model accurately predicted that Dolphins running back Raheem Mostert's disappointing follow-up to a breakout 2023 season. It also called C.J. Stroud's down year, predicted Jayden Daniels' breakout campaign and projected James Cook to become one of Fantasy football's elite running backs in 2024.

The same model has a proven track record providing Fantasy football tips, identifying A.J. Brown as a sleeper in 2020, nailing Jonathan Taylor's monstrous season in 2021 and correctly predicting C.J. Stroud would take a step back in 2024. Additionally, it's called past Fantasy football sleepers like Derrick Henry in 2019, Christian McCaffrey and Alvin Kamara in 2018 and Davante Adams in 2017. 

Now, SportsLine has simulated the entire NFL season 10,000 times and released its latest Fantasy football positional rankings 2025, along with plenty of sleepers, breakouts and busts at every position. Head to SportsLine now to see them

Top 2025 Fantasy football QB rankings

Here's a look at SportsLine's top 2025 Fantasy football QB picks:

1. Lamar Jackson, Baltimore Ravens: Jackson is coming off his first QB1 Fantasy season since 2019, leading all quarterbacks with 915 rushing yards while ranking tenth in rushing touchdowns. He finished with a career-best 4,172 passing yards and 41 touchdowns, ranking first in yards per attempt. The Ravens did not have much offensive turnover this offseason and added veteran wideout DeAndre Hopkins, so Jackson remains the QB1 in the model's rankings.

2. Josh Allen, Buffalo Bills: Allen has been the most consistent Fantasy quarterback in recent years, finishing no worse than QB3 in Fantasy points per game since 2020. He had 12 rushing touchdowns while ranking fifth in rushing yards and third in red-zone carries per game last season. He was the QB2 in Fantasy points per game, which is where the model has him heading into the 2025 season.

3. Joe Burrow, Cincinnati Bengals: Burrow rounds out the top three after posting a QB3 finish last year, recording career highs in almost every statistical category. He led the league in passing attempts, passing yards and passing touchdowns. Burrow is expected to see a similar volume this year, so he should be a strong Fantasy quarterback yet again. See more top QBs here.

Top 2025 Fantasy football RB rankings

Here's a look at SportsLine's top 2025 Fantasy football RB picks:

1. Saquon Barkley, Philadelphia Eagles: Barkley wasted little time proving his worth with his new team last year. After signing as a free agent in the offseason, he helped propel the Eagles to a Super Bowl championship. Reinvigorated, he played in 16 games and had a career-best 2,005 yards rushing on 345 carries (5.8 average) and 13 touchdowns. He also caught 33 passes for 278 yards (8.4 average) and two touchdowns.

2. Bijan Robinson, Atlanta Falcons: The third-year player from Texas has been explosive. In 34 career games, he has rushed for 2,432 yards and 18 touchdowns. He also has 119 receptions for 918 yards (7.7 average) and five touchdowns. He had five games with 100 or more rushing yards and scored two touchdowns in five more. In a 44-38 season-ending overtime loss to the Carolina Panthers, he carried 28 times for 170 yards (6.1 average) and two scores.

3. Jahmyr Gibbs, Detroit Lions: The 23-year-old had a breakout season in 2024. He played in all 17 games, carrying 250 times for 1,412 yards (5.6 average) and 16 touchdowns. In the 45-31 divisional round loss to the Washington Commanders, Gibbs carried just 14 times, but still rushed for 105 yards (7.5 average) and two touchdowns. In a 31-9 win over the Minnesota Vikings in the regular-season finale, he carried 23 times for 139 yards (6.0 average) and three scores. He also caught five passes for 31 yards and one touchdown. See more top RBs here.

Top 2025 Fantasy football WR rankings

Here's a look at SportsLine's top 2025 Fantasy football WR picks: 

1. Ja'Marr Chase, Cincinnati BengalsThere were concerns this offseason that Chase might lose his running mate, Tee Higgins, to free agency. But with Higgins now signed to an extension, the Bengals' offensive trio -- Chase, Higgins, and quarterback Joe Burrow -- remains intact and dangerous. Chase dominated after the catch last season, leading all NFL receivers with 737 yards after the catch. He also secured the receiving triple crown, posting 127 receptions, 1,707 yards, and 17 touchdowns.

2. Malik Nabers, New York Giants: 
Despite missing two games and working within a struggling Giants offense, Nabers impressed in his rookie season with 109 catches, 1,204 yards, and seven touchdowns. New York is banking on Russell Wilson, Jameis Winston, and rookie Jaxson Dart to provide an upgrade at quarterback over last year's group of Daniel Jones, Drew Lock, and Tommy DeVito. Regardless of who's under center, Nabers is a dynamic weapon who's poised to take a leap in Year Two.

3. CeeDee Lamb, Dallas Cowboys: Lamb posted 101 catches for 1,194 yards and six touchdowns last season, despite missing two games and playing half the year without Dak Prescott. While those numbers fell short of his monster 2023 campaign (135 catches, 1,749 yards, 12 TDs), they highlight his consistency. With Prescott healthy, Lamb has a strong chance to return to elite production levels. See more top WRs here.

Top 2025 Fantasy football TE rankings

Here's a look at SportsLine's top 2025 Fantasy football TE picks:

1. Brock Bowers, Las Vegas Raiders: It's hard to imagine a player improving off a record-breaking season, but given likely stronger quarterback play in Las Vegas this season, Bowers could be in a better position to succeed. The Raiders traded for Geno Smith, a significant improvement over the Raiders' quarterbacks last year, when Bowers still set the NFL rookie record for receptions (112) while leading all tight ends with 1,194 yards. The No. 13 overall pick in the 2024 NFL Draft should be the top pass-catcher in the Las Vegas offense again this season, and with improved quarterback play, the model sees Bowers as the top tight end option in 2025 Fantasy football drafts.

2. George Kittle, San Francisco 49ers: The 49ers have been hit hard yet again with preseason injuries, but Kittle and his smelling salts are all set for Week 1. The 31-year-old tight end could be the biggest beneficiary of the rash of injuries as he continues to showcase his strong chemistry with Brock Purdy. Kittle had the second-most receiving yards (1,106) and touchdowns (eight) of his eight-year career last year, and with no signs of slowing down, the model views him as a top tight end option yet again this season.

3. Trey McBride, Arizona Cardinals: If anyone is a safe bet to increase their touchdown total from last season, it's McBride. The 25-year-old tight end had only two receiving touchdowns last season, and yet, he still finished as the TE2 in Fantasy football after posting 1,146 receiving yards. McBride was fourth in the NFL in receptions (111), and he'll remain a top option for Kyler Murray. He has arguably the highest floor of any tight end in Fantasy football, and the near certainty of more touchdowns raises his ceiling as well. See more top TEs here.

Top 2025 Fantasy football defense rankings 

Here's a look at SportsLine's top three 2025 Fantasy football D/ST picks:

1. Philadelphia Eagles D/ST: Howie Roseman is one of the NFL's best executives but his turnaround of the Philadelphia pass defense from 2023 to 2024 was masterful. They went from ranking 30th in points allowed and 26th in yards allowed to ranking second in scoring defense and first in total defense in just one offseason. Now most of the key pieces from that unit return.

2. Baltimore Ravens D/ST: Baltimore had the best run defense in football last season and should have an improved secondary after drafting Malaki Starks in the first round and signing Jaire Alexander. They've got high-level playmakers at every level in Kyle Van Noy, Roquan Smith and Kyle Hamilton.

3. Minnesota Vikings D/ST: They were the No. 5 scoring defense in the NFL last season and they led the NFL with 33 takeaways. Minnesota also scored three defensive touchdowns, and even if the takeaway numbers can't be relied on, the boom potential here is too high to ignore. See more top D/ST here

Top 2025 Fantasy football kicker rankings

Here's a look at SportsLine's top 2025 Fantasy football K picks: 

1. Brandon Aubrey, Dallas Cowboys: Aubrey has the biggest leg in the league and he tied for second in the NFL in points (150) last season. He's 76-of-85 on field goals the last two seasons and he's a staggering 24-of-27 from 50 yards or more.

2. Matt Gay, Washington Commanders: Jayden Daniels is the rising tide that lifts all boats and this offense looks primed to be even better in 2025 after the offseason additions of Laremy Tunsil and Deebo Samuel. Gay was perfect from inside of 50 yards last season and closed the year strong, with 24 points in the final two games of the regular season.

3. Tyler Bass, Buffalo Bills: Despite only making 82.8% of his field goal attempts, Bass finished tied for ninth in scoring (131 points). He was perfect on field goals of more than 50 yards and also locked in during the 2025 NFL playoffs, going 6-for-6 overall.

How to find proven 2025 Fantasy football rankings

SportsLine has ranked almost every Fantasy-relevant player at every position and you can see their entire 2025 Fantasy football positional rankings now. You can only see their top sleepers, breakouts and busts at every position at SportsLine.

So who are the top players at every position and who is being underrated? Visit SportsLine now to get 2025 Fantasy Football cheat sheets for every single position, all from the model that regularly outperforms human rankings.