Duren (ankle) has been ruled out for Wednesday's game against Portland.
Duren was initially listed as questionable and didn't participate in the team's morning shootaround, so this isn't a major surprise. However, it is a huge blow, as the second-year center was off to a fast start this season. In Duren's absence, Marvin Bagley will likely start at canter, while James Wiseman could also see his first action of the campaign.